Like a long awaited momentum, Human disbelieve or believe in possible Spontaneous Mutation is more than ever ‘the Time’ subject, and FLIX such as “Annihilation” (Alex Garland) only play its role in disclosing the not so pleasant truth of it, Mutation is a tans-Time occurrence which bend’s the fabric of Space revealing the very real fragility of Our perceivable Biology.
The HOB DNA Etc … – MAR 2018
MUTATION’s – or the Paradox of Biological Existence
Mutating We have been, Are and will Be!
Nothing stay the same, observations dictate changes. In order to pursue Our comprehension of the phenomenon as we don’t give in the Race Archetype at the HOB, we consider it unfounded as per today, we will direct our attention to the Eso-Centric Nature of Mutation, and with regards to Biological Mutation it is necessary to define its Place and Time.
Earth: Planetary object revolving around a Class G2V Star (Possibly shifting toward G4V), Human inhabited – .0 Planetary Civilization or L0ose Civilization (for Level 0 of social evolution Civilization), Year 2018 according to the Gregorian calendar count, Planet inhabitant approximates 8 billions, endangered Biotic environments, Humanity unmanaged Cell entropy is the first cause of mortality, Planet Geostasis uncontrolled, fragile Nutritional resources sustainability, potable Water quality and quantity deplenishing and Conscious Awareness is surpassed by a fear/Greed dichotomy states.
Human, known quality – LINNAEAN CLASSIFICATION
| Kingdom: Animalia
What are We talking about?
We are talking real time HEME (Human Enhancement Mutation Event), not months or Years, but instantaneous Light speed driven event.
Possibility of Mutation is slowly taking reality shapes and without ambiguity Human of Earth won’t be exempt from the shift. Not so far away from reality but away from comic cons, Our very Biological reality is providing with an elevated dimension in a complex retribution of “the Kind”, the Human one.
The HOB is inviting You to consider (or re-consider) the very real application of Mutation in its most primal form, Eso-Bio-Centric and Misanthropic in Nature, the term itself demand caution and acceptance of an extravagant Creativity. Biological creativity.
What do We know of it – Types of mutations
There are many different ways that DNA can be changed, resulting in different types of mutation. Here is a quick summary of a few of these:
A substitution is a mutation that exchanges one base for another (i.e., a change in a single “chemical letter” such as switching an A to a G). Such a substitution could:
1. change a codon to one that encodes a different amino acid and cause a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.
2. change a codon to one that encodes the same amino acid and causes no change in the protein produced. These are called silent mutations.
3. change an amino-acid-coding codon to a single “stop” codon and cause an incomplete protein. This can have serious effects since the incomplete protein probably won’t function.
Insertions are mutations in which extra base pairs are inserted into a new place in the DNA.
Deletions are mutations in which a section of DNA is lost, or deleted.
Since protein-coding DNA is divided into codons three bases long, insertions and deletions can alter a gene so that its message is no longer correctly parsed. These changes are called frameshifts.
For example, consider the sentence, “The fat cat sat.” Each word represents a codon. If we delete the first letter and parse the sentence in the same way, it doesn’t make sense.
In frameshifts, a similar error occurs at the DNA level, causing the codons to be parsed incorrectly. This usually generates truncated proteins that are as useless as “hef atc ats at” is uninformative.
There are other types of mutations as well, but this short list should give you an idea of the possibilities.
Outer Causes! Cosmic influences
-The hypothesis of Sapir Whorf is known to influence Brain Mutation according to the systematic Language and Social Environment it is surrounded with, would it work the same with a Mutating Physical environment?-
EXTRACT ”Subsequent investigations added the next crucial pieces to the jigsaw puzzle. Scientists stumbled on the truth that air molecules would conduct electricity once ionized by X-rays or charged particles. The question of course still remained, where had the sufficiently energised particles come from, that had so powerfully penetrated the lead-lined chamber and so affected De Coulomb’s charged sphere? The answer came at last, over a century later. During a hot air balloon flight in August 1912 that brought him to Bad Saarow in Brandenburg, Germany, Viktor Hess took a number of readings with an ionisation chamber that showed ionising radiation significantly increased the higher he flew. Although on the ground our planet was known to display some naturally-occurring radioactivity, at the balloon’s maximum altitude of 5350m Hess recorded ionizing radiation magnitudes three times that found at sea level. The conclusion from these measurements was self-evident. The farther one moved away from the Earth’s surface, or rather, the closer one moved toward space, the greater the count of high energy charged particles.”// here
DNA: The molecular basis of mutations
Since mutations are simply changes in DNA, in order to understand how mutations work, you need to understand how DNA does its job. Your DNA contains a set of instructions for “building” a human. These instructions are inscribed in the structure of the DNA molecule through a genetic code. It works like this:
DNA is made of a long sequence of smaller units strung together. There are four basic types of unit: A, T, G, and C. These letters represents the type of base each unit carries: adenine, thymine, guanine, and cytosine.
The sequence of these bases encodes instructions. Some parts of your DNA are control centers for turning genes on and off, some parts have no function, and some parts have a function that we don’t understand yet. Other parts of your DNA are genes that carry the instructions for making proteins — which are long chains of amino acids. These proteins help build an organism.
The causes of mutations
After the protein is built based on the sequence of bases in the gene, the completed protein is released to do its job in the cell.
1. DNA fails to copy accurately
Most of the mutations that we think matter to evolution are “naturally-occurring.” For example, when a cell divides, it makes a copy of its DNA — and sometimes the copy is not quite perfect. That small difference from the original DNA sequence is a mutation.
2. External influences can create mutations
Mutations can also be caused by exposure to specific chemicals or radiation. These agents cause the DNA to break down. This is not necessarily unnatural — even in the most isolated and pristine environments, DNA breaks down. Nevertheless, when the cell repairs the DNA, it might not do a perfect job of the repair. So the cell would end up with DNA slightly different than the original DNA and hence, a mutation.
Protein-coding DNA can be divided into codons — sets of three bases that specify an amino acid or signal the end of the protein. Codons are identified by the bases that make them up — in the example at right, GCA, for guanine, cytosine, and adenine. The cellular machinery uses these instructions to assemble a string of corresponding amino acids (one amino acid for each three bases) that form a protein. The amino acid that corresponds to “GCA” is called alanine; there are twenty different amino acids synthesized this way in humans. “Stop” codons signify the end of the newly built protein.
The effects of mutations
Since all cells in our body contain DNA, there are lots of places for mutations to occur; however, some mutations cannot be passed on to offspring and do not matter for evolution. Somatic mutations occur in non-reproductive cells and won’t be passed onto offspring. For example, the golden color on half of this Red Delicious apple was caused by a somatic mutation. Its seeds will not carry the mutation.
The only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations.
Effects of Germ line Mutations
A single germ line mutation can have a range of effects:
1. No change occurs in phenotype.
Some mutations don’t have any noticeable effect on the phenotype of an organism. This can happen in many situations: perhaps the mutation occurs in a stretch of DNA with no function, or perhaps the mutation occurs in a protein-coding region, but ends up not affecting the amino acid sequence of the protein.
2. Small change occurs in phenotype.
A single mutation caused this cat’s ears to curl backwards slightly.
3. Big change occurs in phenotype.
Some really important phenotypic changes, like DDT resistance in insects are sometimes caused by single mutations. A single mutation can also have strong negative effects for the organism. Mutations that cause the death of an organism are called lethals — and it doesn’t get more negative than that. credit
Little mutations with big effects: Mutations to control genes
EXTRACT “Mutations are often the victims of bad press — unfairly stereotyped as unimportant or as a cause of genetic disease. While many mutations do indeed have small or negative effects, another sort of mutation gets less airtime. Mutations to control genes can have major (and sometimes positive) effects.
Some regions of DNA control other genes, determining when and where other genes are turned “on”. Mutations in these parts of the genome can substantially change the way t Many organisms have powerful control genes that determine how the body is laid out. For example, Hox genes are found in many animals (including flies and humans) and designate where the head goes and which regions of the body grow appendages. Such master control genes help direct the building of body “units,” such as segments, limbs, and eyes. So evolving a major change in basic body layout may not be so unlikely; it may simply require a change in a Hox gene and the favor of natural selection.he organism is built. The difference between a mutation to a control gene and a mutation to a less powerful gene is a bit like the difference between whispering an instruction to the trumpet player in an orchestra versus whispering it to the orchestra’s conductor. The impact of changing the conductor’s behavior is much bigger and more coordinated than changing the behavior of an individual orchestra member. Similarly, a mutation in a gene “conductor” can cause a cascade of effects in the behavior of genes under its control.”
As True or not this maybe, the ideology of the Nature “Cells” providing with an Evolution scenarios selection makes Us all unique, as Present Being. But what really disturbs Us is the possibility that We won’t Be selected further on the story of Life.
What was before a supposed Big-Bang and what was before the first Cell is but the same, and it is often rejected for the simple reason that it demands Us to face the unknown, Our unknown. Conscious Life is as precious as We can imagine it to Be, and if any shift has been, Is or to become, Humanity is at an Edge for which not ‘if’ but rather ‘when’ Mutation will be Consciously realized and accepted.
Anticipation FLIX like “Annihilation” provides us with extensive paralleled possibilities, but it does not offer Us the perspective of an Ex-Nihilo experience, to the contrary. Biologist Researcher and Lecturer Adam Rutherford participation to numerous movies on the ‘Genre’ only point out that Our existence, so far, is contain within the very dependable Biologic speed of Light (in reality and creativity) and does not allow Us to wonder beyond. Evidence of limitation?
Matter is, it would only takes a shift in Photon medium construct to reshape what We see and perceive as Our reality.
As it appear to be, Human’s are strongly attached to their actual and factual appearances, and if Consciousness prevails (*Quantum Observation), the Consciousness of Mutation must be for Life to Be and Conscious Co-Creation may Be the answer to that, after all consideration, all is made of a single Cell,…
… if all is made at all!
toward an Ethical Consciousness and a Planetary Civilization
the HOB DNA Etc …. – MAR 2018